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Marchiafava–Bignami disease
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Marchiafava–Bignami disease : ウィキペディア英語版
Marchiafava–Bignami disease

Marchiafava–Bignami disease is a progressive neurological disease of alcoholism, characterized by corpus callosum demyelination and necrosis and subsequent atrophy.
==Eponym==
It was first described in 1903 by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker.〔E. Marchiafava, A. Bignami. Sopra un' alterazione del corpo calloso osservata da sogetti alcoolisti. Rivista di patologia nervosa e mentale, 1903, 8 (12): 544–549.〕 In this patient, Marchiafava and Bignami noticed that the middle two-thirds of the corpus callosum were necrotic.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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